Bacterial Topoisomerase II

《英文msh詞典》Bacterial Topoisomerase II
[入口詞] Bacterial Topoisomerase II
[主題詞] DNA Topoisomerases,Type II,Bacterial
[英文釋義] Bacterial enzymes of the DNA TOPOISOMERASES TYPE II class that catalyze ATP-dependent breakage of both strands of DNA,passage of the unbroken strands through the breaks,and rejoining of the broken strands. These enzymes bring about relaxation of the supercoiled DNA duplex. Bacterial DNA topoisomerases in the Type II class exist as heterotetramers of 2 subunits,such as 2 gyrA and 2 gyrB in DNA GYRASE.